白细胞介素,简称白介素,是指在白细胞或免疫细胞间相互作用的淋巴因子,它和血细胞生长因子同属细胞因子。两者相互协调,相互作用,共同完成造血和免疫调节功能。白细胞介素在传递信息,激活与调节免疫细胞,介导T、B细胞活化、增殖与分化及在炎症反应中起重要作用。
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【文献标题】Differences in pig respiratory tract and peripheral blood immune responses to Actinobacillus pleuropneumoniae
【作者】Chuntong Bao,Hexiang Jiang,Rining Zhu,et.al
【作者单位】吉林大学(Jilin University)
【文献中引用产品】
猪白细胞介素1α(IL-1α )ELISA试剂盒
猪白细胞介素1β(IL-1β)ELISA试剂盒
猪白细胞介素1受体拮抗剂(IL-1Ra)ELISA试剂盒
猪白细胞介素2(IL-2)ELISA试剂盒
猪白细胞介素3(IL-3)ELISA试剂盒
猪白细胞介素4(IL-4)ELISA试剂盒
猪白细胞介素5(IL-5)ELISA试剂盒
猪白细胞介素6(IL-6)ELISA试剂盒
猪白细胞介素8(IL-8)ELISA试剂盒
猪白细胞介素2(IL-10)ELISA试剂盒
猪白细胞介素12(IL-12)ELISA试剂盒
猪白细胞介素13(IL-13)ELISA试剂盒
猪白细胞介素15(IL-15)ELISA试剂盒
猪白细胞介素-17A(IL-17A) ELISA试剂盒
猪白细胞介素18(IL-18)ELISA试剂盒
猪白细胞介素21(IL-21)ELISA试剂盒
猪白细胞介素22(IL-22)ELISA试剂盒
猪白细胞介素23(IL-23)ELISA试剂盒
猪白细胞介素32(IL-32)ELISA试剂盒
猪肿瘤坏死因子α(TNF-α)ELISA试剂盒
猪单核细胞趋化蛋白1(MCP-1/CCL2/MCAF)ELISA试剂盒
猪巨噬细胞炎性蛋白1β(MIP-1β/CCL4)ELISA试剂盒
猪正常T细胞表达和分泌因子(RANTES/CCL5)ELISA试剂盒
猪粒细胞巨噬细胞集落刺激因子(GM-CSF)ELISA试剂盒
猪α干扰素(IFN-α)ELISA试剂盒
猪干扰素诱导蛋白10(IP-10)ELISA试剂盒
猪转化生长因子β(TGF-β)ELISA试剂盒
猪CXC趋化因子配体9(CXCL9)ELISA试剂盒
猪趋化因子CCL3样蛋白1(CCL3L1)ELISA试剂盒
【DOI】https://doi.org/10.1016/j.vetmic.2020.108755
【出版期刊】《Veterinary Microbiology》
【影响因子(IF)】 3.0
【产品原文引用】
Cytokine measurements
Blood was collected from animals at 0/6/12/24/48/120 h post infection (n=3 each time point),incubated at 4°C for 30 min, and sera obtained after centrifugation. The sera and BALF from the same group were mixed together in equal proportion. Clear non-hemolyzed sera and BALF were stored at -80°C prior to biological analyses. The levels of IL-1α, IL-1β, IL-1Ra, IL-2, IL-3, IL-4,IL-5, IL-6, IL-8, IL-10, IL-12, IL-13, IL-15, IL-17A, IL-18, IL-21, IL-22, IL-23, IL-32, TNF-α,CCL2(MCP-1), CCL4 (MIP-1β), CCL5 (RANTES), GM-CSF, IFN-α, IP-10, TGF-β, CXCL9 and CCL3L1 were determined by ELISA according to the manufacturer’s protocols (Shanghai Jinma Biotechnology Co. Ltd.). The mixed sample had three technical replicates. A sample diluent was used to dilute the mixed sera and BALF samples five times according to the kit instructions, no other dilution was investigated.